Wednesday, October 25, 2006
what an ass
"He is exaggerating the effects of the disease," Limbaugh told listeners. "He's moving all around and shaking and it's purely an act. . . . This is really shameless of Michael J. Fox. Either he didn't take his medication or he's acting."
Right, cause none of those are the effects of disease....aagh!
Monday, October 23, 2006
i missed this last week...
Friday, October 20, 2006
Oh me Oh My
Again, things get so complicated as we get older huh!?
The only silence I get is when I am asleep
Yet I crave to know when I will catch my breath rest my head without being asleep.
Thursday, October 19, 2006
okay, so, I have been listening to imogen heap for about two years now...and their new album came out on the 16th...I realized come the 13th that i was half counting the days...I do not think i have had a favoirite band in some time...they are really creative and thoughtful...yep I like them.
Tuesday, October 17, 2006
Monday, October 16, 2006
no money in my pocket - YO!
Saturday, October 14, 2006
saw arturo ui last night. ah, whoa...wow! scot wastes nothing - all is ui. i was not ready or wanting for it to end - i mean i knew it must. the whole movie feel... i am at a play - yet it costs as much as a movie - and oh, i smell popcorn...i felt it was shameful in some way at first - raised my brow. But, man it works the whole package of the evening worked.
go - go to it now...
Thursday, October 12, 2006
Wednesday, October 11, 2006
does metro think of people as cars?
i seriously spent 4 hours on metro today. it was for a good cause - but none the less I read the entire express and two short stories in the book i am reading.
On the back of the express today they had this metro newsletter of sorts...in the bottom column entitled metro buzz - they had this to say: " with smarTrip only aisles, 32 customers can pass through a fare gate each minute, compared to 22 per minute currently. The SmarTrip express lanes are similar to E-ZPass lanes on toll roads." They are thinking of people as cars - right...that is really disturbing to me.
Tuesday, October 10, 2006
best thing said to me today
okay, this may be a bit of rant...but here goes. Why do humans always need to compete? What is that? Now, I am not saying that I am not competitive – I am to a point – but without real respect for oneself and human nature mixed in with that competitiveness – oh, my what a bad trait this is. This type of person seriously makes my skin crawl – like used car dealer: never really getting to see the real face of the person – always putting on masks to give people what they want…ick!
Saturday, October 07, 2006
the best health news!
The compound may protect the brain |
Scientists showed a synthetic version of the compound may reduce inflammation associated with Alzheimer's and thus help to prevent mental decline.
They hope the cannabinoid may be used to developed new drug therapies.
The research, by Madrid's Complutense University and the Cajal Institute, is published in the Journal of Neuroscience.
The scientists first compared the brain tissue of patients who died from Alzheimer's disease with that of healthy people who had died at a similar age.
They looked closely at brain cell receptors to which cannabinoids bind, allowing their effects to be felt.
They also studied structures called microglia, which activate the brain's immune response.
Microglia collect near the plaque deposits associated with Alzheimer's disease and, when active, cause inflammation.
The researchers found a dramatically reduced functioning of cannabinoid receptors in diseased brain tissue.
This was an indication that patients had lost the capacity to experience cannabinoids' protective effects.
The next step was to test the effect of cannabinoids on rats injected with the amyloid protein that forms Alzheimer's plaques.
Those animals who were also given a dose of a cannabinoid performed much better in tests of their mental functioning.
The researchers found that the presence of amyloid protein in the rats' brains activated immune cells.
However, rats that also received the cannabinoid showed no sign of microglia activation.
Using cell cultures, the researchers confirmed that cannabinoids counteracted the activation of microglia and thus reduced inflammation.
Drug target
Researcher Dr Maria de Ceballos said: "These findings that cannabinoids work both to prevent inflammation and to protect the brain may set the stage for their use as a therapeutic approach for Alzheimer's disease."
Dr Susanne Sorensen, head of research at the Alzheimer's Society, said: "This is important research because it provides another piece of the jigsaw puzzle on the workings of the brain.
"There is no cure for Alzheimer's disease, so the identification of another target for drug development is extremely welcome.
"The Alzheimer's Society looks forward to seeing further research being carried out on cannabinoid receptors as drug targets for Alzheimer's disease but would warn the public against taking marijuana as a way of preventing Alzheimer's.
"It is now generally recognised that as well as providing a 'high', long-term use of marijuana can also lead to depression in many individuals."
Different receptors
Harriet Millward, of the Alzheimer's Research Trust, said there were two main types of cannabinoid receptor, CR1 and CR2.
"It is CR1 that produces most of the effects of marijuana, including the harmful ones.
"If it is possible to make drugs that act only on CR2, as suggested by the authors of this study, they might mimic the positive effects of cannabinoids without the damaging ones of marijuana.
"However, this is a fairly new field of research and producing such selective drugs is not an easy task.
"There is also no evidence yet that cannabinoid-based drugs can slow the decline in human Alzheimer's patients."Friday, October 06, 2006
random thoughts
Who tattoos their face?
I saw Dan T. on the metro last night.
Why are relationships so complicated as one gets older…oh, the baggage we carry.
My oven doesn’t work.
I really am loving U2 more that usual.
I think I need to go on a trip.
I should recycle paper more.
Fall is a great season.
Am I supposed to own where I live? This really has never crossed my mind…no joke.
It will be a cold winter.
Amish shooting!
Fenty and Dan T…it feels like
I really do not drink beer.
Why does the heat just turn on in my house?
I need office furniture. Anyone!!!???
Leggings are good!
My home is the USA
I need to go to
Hitler was crazy..yet really fucking brilliant
Thursday, October 05, 2006
who i want to meet
I have read nearly all of Haruki Murakami novels and short stories. I am powering through the 24 short stories in Blind Willow Sleeping Woman. There is something about his writing that is at one point so familiar - like a thought you had but never came up with quite the right words to express perhaps - or maybe not even formed it into a thought cause words were not what it was - in saying all of that his stories are also surprising and take you on such a journey. It is like a dream when you first wake up you remember portions - splashes and all day you keep going back to it all day to connect the dots.
I do not have a lot of time to read....or at least to way I woudl like to. I do wish and hope that some day I could meet Haruki and talk to him about his process.
Sunday, October 01, 2006
best thing said to me today
Listen to this song. Click on the first link sandbag search:http://www.luciditysuitcase.com/music.html
this is from a show called earth's sharp edge. in the scene where this song is played a man's suitcase is being searched by airposrt security- inside they find sand. Once the sand is poured out the man whos suitcase it is walks a small camel over the pile of sand on the table - slowly - it is one part beauitful and another part heart wrenching as you know his homeland - how he knew is gone forever.